A16z Podcast

What happens when a startup becomes a giant—and then has to reinvent itself all over again?In this episode, Martin Casado sits down with Raghu Raghuram (former CEO of VMware) and Jeetu Patel (President and CPO at Cisco) for a deep, tactical conversation on scaling, disruption, and navigating transformation from the inside. They share hard-won lessons from leading two of the most iconic infrastructure companies in tech—through waves like virtualization, cloud, containers, and now AI.They cover:How to keep innovation alive inside large companiesWhy the best companies operate with a founder’s mindset, even without foundersThe difference between selling to buyers vs. practitionersWhy the story is the strategy, and how to tell it at scaleHow Cisco is rebuilding its startup DNA in the age of AIIf you're building or leading through a major tech wave, this episode is a playbook. Timecodes:0:00 Introduction 2:02 Weapons of Mass Disruption: Abstractions, Business Models, and Cloud  5:57 Cisco’s Missed Cloud Wave &