A16z Podcast

What if now is the best time in decades to start a company?In this episode, taken from Speedrun, a16z’s accelerator for early-stage founders, Marc Andreessen joins games General Partner Jonathan Lai to make the case that we’re entering a once-in-a-generation window for innovation. From the rise of AI to the cultural and policy shifts reshaping the global economy, Marc explains why the next four years present a rare opportunity for builders to seize the moment.Along the way, they discuss market timing, platform shifts, and what sets successful founders apart - including lessons from Steve Jobs, insights into AI’s impact on storytelling and games, and why being “too early” can feel just like being wrong.Timecodes0:00 Lessons from Steve Jobs on Leadership & Innovation2:27 The AI Boom: How It’s Changing Everything5:52 Market Timing: The #1 Factor in Startup Success8:13 Why the Next 4 Years Are Critical for Tech11:30 AI & The Future of Gaming, Storytelling & Virtual Worlds14:28  Why Some Startups Fail