A16z Podcast

Taking a company from idea to household name is always difficult. But the past few years presented challenges that caught even the most-seasoned CEOs off guard.In this episode, you’ll hear from two CEOs that navigated these waters and somehow, came out on the other side. These recordings come straight from our exclusive Connect/Enterprise event, bringing together top executives across the a16z network. Resources:Additional content from Connect/Enteprise:Enterprise Startups: Advice on Hiring, Firing, Scaling, and SellingBuilding Products With Generative AI Learn more about company-building: https://a16z.com/category/company-building/ Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used

Fei-Fei Li, PhD,  Professor in the Computer Science Department at Stanford University, and Co-Director of Stanford’s Human-Centered AI Institute, joins Bio + Health founding partner Vijay Pande.In this candid conversation, Li unfolds her transformation from a young immigrant to an influential figure in AI. The conversation explores the birth of ImageNet, a pivotal step that bridged the gap between visual intelligence and accessible AI technology. They delve into the notion of a 'Dignity Economy,' hinting at a future where technology serves to elevate human experience rather than undermine it. Li also touches on the delicate balance between relentless innovation and life's humble pursuits. This episode peels back the layers on the human side of AI, offering a rare glimpse into the personal and professional realms of a pioneer shaping the AI landscape.Check out her new book, The Worlds I See, here: https://us.macmillan.com/books/9781250897930/theworldsiseeCheck out other episodes form our sister podcast, Bio Ea

Is it possible to construct a virtual society that authentically replicates human behavior? AI Town, a virtual town experiment where AI residents live, interact, and engage, provides valuable insights into the future of AI's believability and its interaction with humanity.In this panel discussion, Joon Park, the author of 'Generative Agents: Interactive Simulacra of Human Behavior,' and Martin Casado from a16z, discuss  the influence and potential of Generative Agents, exploring their practical applications in the real world.Topics Covered00:00 - Simulating human behaviors04:49 - What are generative agents?07:47 - Simulations, new technology, and LLMs11:45 - The architecture behind simulating human behavior16:37 - Generative agents interactions: observing, planning, and reflecting20:22 - What is the value in advancing generative agents?24:01 - Use cases for simulation behavior technology29:31 - What are the ethical frameworks?33:12 - Q&A from the audience Resources: Find AI Town: https://www.convex.dev/ai

Software crosses borders effortlessly. The globalization of money, however, is considerably more challenging. This is especially true for multinational businesses, which grapple with managing multiple accounts in diverse currencies, navigating costly foreign exchange rates, and unpredictable money transfers.As businesses increasingly embrace a global default, top fintech entrepreneurs are rising to the challenge, addressing cross-border infrastructure issues and offering comprehensive solutions.In this episode, a16z partners Angela Strange, Joe Schmidt, and Gabriel Vasquez discuss the challenges of cross-border payment infrastructures and what fintech entrepreneurs are doing to create a more integrated, financially inclusive world.Topics Covered:00:00 - Software crosses borders easily; money does not. 03:02 - Why has global payments been a challenge for so long? 05:44 - How global payments and money currently moves07:25 - The metrics used to measure a country's financial health12:13 - The impact of regulation

Subscribe to The Ben & Marc Show on Apple Podcasts: https://bit.ly/3SdsfNtSubscribe to The Ben & Marc Show on Spotify: https://spoti.fi/3SclPOrRead the full manifesto: https://a16z.com/the-techno-optimist-manifesto/ This past week, Marc released his new vision for the future – “The Techno-Optimist Manifesto”.In an article that has sparked widespread conversation across traditional and social media, Marc challenges the pessimistic narrative surrounding technology today, and instead celebrates it as a liberating force that can lead to growth, progress and abundance for all. In this one-on-one conversation based on YOUR questions from X (formerly Twitter), Ben and Marc discuss how technological advancements can improve the quality of human life, uplift marginalized communities, and even encourage us to answer the bigger questions of the universe.We hope you’ll be inspired to join us in this Techno-Optimist movement. Enjoy! Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn:

As VR technology inches forward, completely new experiences loom on the horizon.In today’s episode, we expose listeners to the very real-world use cases already present on these devices, from fitness to education.First up is Gym Class VR, one of the top-rated apps on the Quest. Cofounder, Paul Katsen, shows us how to dribble and dunk in the metaverse, but more importantly, discusses the social impact of VR, the technological prerequisites to get there, and the role of AI as we progress.Following on is a founder on a mission to revolutionize education. Anurupa Ganguly from Prisms VR, explores how virtual reality has the potential to close the gap – one where 70% of US 8th graders are not proficient in foundational math.Head over to our YouTube channel to see two a16z Podcast firsts: a full interview in VR, and host Steph slam dunking on an NBA court. Topics Covered: 00:00 - The current state of VR03:38 - How do you build the #1 VR app?05:56 - How will VR become an everyday activity?07:37 - The social and the t

Today’s episode continues our coverage from a16z’s recent AI Revolution event. You’ll hear directly from a16z cofounder Ben Horowitz and Databricks cofounder and CEO, Ali Ghodsi as they answer questions around AI and the enterprise, plus their perspectives on open source, whether benchmarks are BS, and the scramble of universities to take part in the very wave they kicked off decades ago.If you’d like to access all the talks from AI Revolution in full, visit a16z.com/airevolution. Resources:Find Ali on Twitter: https://twitter.com/alighodsiFind Ben on Twitter: https://twitter.com/bhorowitzCheck out Databricks: https://twitter.com/databricks Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or

Today’s episode continues our coverage from a16z’s recent AI Revolution event. You’ll hear a16z Bio & Health GP Vijay Pande speak with Daphne Koller about the fascinating convergence of machine learning and genomics – two industries that have benefitted decades of investment and progress – which are now colliding head on.Daphne is a prominent innovator at this intersection, as a long-time professor in computer science at Stanford and co-founder of Coursera, who has decided to step back into the arena with her company Insitro. In fact, Insitro is a blend of in silico and in virto!If you’d like to access all the talks from AI Revolution in full, visit a16z.com/airevolution. Resources:Find Daphne on Twitter: https://twitter.com/DaphneKollerFind Vijay on Twitter: https://twitter.com/vijaypandeFind Insitro on Twitter: https://twitter.com/insitro Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https:/

The AI Revolution is here. In this episode, you’ll learn what the most important themes that some of the world’s most prominent AI builders – from OpenAI, Anthropic, CharacterAI, Roblox, and more – are paying attention to. You’ll hear discussion around the real-world impact of this revolution, on industries ranging from gaming to design, and the considerations around alignment along the way.This footage is from an exclusive event, AI Revolution, that a16z ran in San Francisco recently. If you’d like to access all the talks in full, visit a16z.com/airevolution. Topics Covered:00:00 - AI Revolution02:39 - Putting technology in users’ hands08:21 - AI alignment and safety21:44 - Future opportunities Resources: Catch the all the talks at https://a16z.com/airevolution Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note th

The AI Revolution is here. In this episode, you’ll learn what the most important themes that some of the world’s most prominent AI builders – from OpenAI, Anthropic, CharacterAI, Roblox, and more – are paying attention to. You’ll hear about the economics of AI, broad vs specialized models, the importance of UX, and whether we can expect scaling laws to continue.This footage is from an exclusive event, AI Revolution, that a16z ran in San Francisco recently. If you’d like to access all the talks in full, visit a16z.com/airevolution. Topics Covered00:00 - AI Revolution01:42 - The economics of AI06:55 - The third epoch of compute13:52 - Recognizing scaling laws17:42 - Can scaling laws continue?22:34 - Potential bottlenecks25:58 - Personalization vs generality29:43 - The importance of UX31:55 - The future of multi-modality Resources:Catch the all the talks at https://a16z.com/airevolution Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscri

The space industry is evolving rapidly, with the cost of launching payloads to orbit dropping significantly. But who's investing in this sector, and how will it evolve? In this episode, we delve into the transformative journey of the satellite industry with Andy Lapsa, co-founder of Stoke Space. With over a decade of experience at Blue Origin, Andy is now at the forefront of sustainable space travel, pioneering fully reusable rockets.Don’t forget to check out Part 1 in this mini series, where we explore the public and private players in space with John Gedmark from Astranis. Resources: Learn more about Stoke: https://www.stokespace.comFind Andy on Twitter: https://x.com/AndyLapsa?s=20 Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as

The cost of launching payloads to orbit has dramatically dropped, igniting a space renaissance. In 2022, a record 186 rocket launches (41 more than the previous year!) underscores this shift.In Part 1 of our satellite economy mini-series, we sit down with John Gedmark, co-founder of Astranis, to reflect on today's innovations, who’s on the other side of the satellite market, the capabilities they’re looking for, competition, and their mission to provide internet access to 4 billion underserved people.Look out for Part 2, where we tackle the challenges of rapidly reusable rockets with Andy Lapsa from Stoke Space. Resources: Learn more about Astranis: https://www.astranis.comFind John on Twitter: https://x.com/Gedmark?s=20 Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational p

with @alive_eth @danboneh @smc90This week's all-new episode covers the convergence of two important, very top-of-mind trends: AI (artificial intelligence) & blockchains/ crypto. These domains together have major implications for how we all live our lives everyday; so this episode is for anyone just curious about, or already building in the space. The conversation covers topics ranging from deep fakes, bots, and the need for proof-of-humanity in a world of AI; to big data, large language models like ChatGPT, user control, governance, privacy and security, zero knowledge and zkML; to MEV, media, art, and much more. Our expert guests (in conversation with host Sonal Chokshi) include: Dan Boneh, Stanford Professor (and Senior Research Advisor at a16z crypto), a cryptographer who’s been working on blockchains for over a decade and who specializes in cryptography, computer security, and machine learning -- all of which intersect in this episode;Ali Yahya, general partner at a16z crypto, who also previously work

With recent landmark legislation being passed around salary transparency, many companies are playing catch up as they interpret and implement changes.In this episode, members of the a16z People Operations team,  Shannon Schiltz and Brandon Cherry explore how companies can best prepare themselves to not just survive, but thrive in this new environment. Topics Covered:00:00 - Salary transparency legislation01:52 - The culture around pay transparency 03:39 - What is the legislation?07:01 - How are companies reacting?11:03 - Structuring a compensation philosophy 12:30 - Pay ranges15:35 - Exceptions to the pay range18:17 - Leveling staff22:30 - Ranges and roles and company growth28:24 - Location based pay30:05 - What should employees look for when applying for work?32:19 - Job postings35:05 - Reviewing compensation ranges 35:42 - At what stage do you hire help? Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast

How many people spend more time organizing their “second brains”, instead of leveraging the information within them? With consumer AI now capable of processing simple language prompts and interfacing with unstructured data, is the landscape of information management on the brink of a transformative evolution?Founders of Mem, Kevin Moody and Dennis Xu, plus writer Nat Eliason, explore what’s gotten in the way of a true second brain, and how AI may finally unlock what “knowledge management” tools have promised for so long.  Topics Covered:00:00 - A true second brain02:45 -  Knowledge management06:01 - Thiago Forte's ‘Building a Second Brain’10:24 - Digital hoarding12:53 - The fun of organizing 14:16 - Levels of utility19:09 - Can the unstructured nature of AI help?21:46 - What does a second brain unlock? 25:23 - Time spent  searching for information31:07: LLMs and technology unlocks34:22 - Personalization 36:24 - Is the second brain a new PA and EA?38:57 - Challenges44:32 - Moats and differentiators  Resources:

In this exclusive conversation from a16z’s Bio and Health BUILD Summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. They discuss everything from the inspiration behind Ben’s book The Hard Thing About Hard Things, how the open Internet was secured, the difference between wartime and peacetime CEOs, scaling culture, and understanding how bio & healthcare differs from other forms of technology. Topics Covered:00:00 - Introduction02:09 - What are the most important lessons for a CEO?08:45 - Surprising leaders in history11:41 - Wartime CEO vs the peacetime CEO14:54 - Cultures role20:59 - Communication and scaling 25:39 - Culture as a moat27:46 - The interplay between startups and incumbents30:22 - Advice for founders on navigating AI Resources:Find Ben on Twitter: https://twitter.com/bhorowitzFind Jorge on Twitter: https://twitter.com/jorgecondebioBen’s Book: https://www.amazon.com/Hard-Thing-About-Things-Building/dp/0062273205 Stay Updated: Find a16z on Twitter: https://twitter.c

From artificial limbs to memory foam, many inventions have emerged from our quest to understand the cosmos. In this episode we explore cosmic history, space's impact on technology, and the enduring human fascination with space exploration. To take us on this journey is astrophysicist John Mather, a Nobel Prize winner for his work on the COBE satellite and a key figure in the James Webb Space Telescope project.Prepare to be intrigued and left with a sense of wonder about the universe's influence on our world. Topics Covered:00:00 –  Innovations through the pursuit of space03:52– John’s early life 06:44 – Proving The Big Bang Theory 13:30 – The mysteries of quantum mechanics15:10 –  Leading the James Webb Telescope17:12 – Images from James Webb20:32 – Are we alone? 24:20 – New telescopes25:18 – Engineering in space for earth29:31 –  What would you like to see solved in your lifetime?32:24 – What came before The Big Bang? 25:04 – Misconceptions about space37:17 – Can humans be a multiplanetary species?38:20 - Pr

With students learning in more places and different ways than we have ever seen, the pace of change in education is dizzying. Can this progress narrow learning gaps exacerbated by COVID-19 or will it fuel divides? How can we make the most of this once-in-a-generation opportunity?Join our panelists from Khan Academy, PrismsVR, and Minecraft Education as we discuss the classroom of the future, and how important technologies including AI, XR, and gaming should play a role in it. Topics Covered:00:00 – The classroom of 202304:30 – Data on the current classroom05:40– Developing the next gen of STEM talent08:00 –  AI in the classroom 13:10 – The role of gaming in the classroom16:00 – Misconceptions of technology in classroom17:51 – The ways teachers and students use AI21:15 - The future role of a teacher24:25 – Personalization and ownership in education27:11 – Getting hardware into the classroom29:54 - Misconceptions of teacher’s abilities and appetite for tech31:25 – Why implement these changes now?36:05 – Call to

With software becoming more important than ever, hardware is following suit.As the world generates more data, unlocking the full potential of AI means a constant need for faster and more resilient hardware. But how much does this all really cost? In this final segment of our AI hardware series, we tackle that question head on. Be sure to check part 1 and 2, where we explore the emerging architectures and the momentous competition for AI hardware. Topics Covered:00:00 – The cost of compute02:20 – Is this sustainable?03:23 – The cost to train a model05:39 – Computation requirements09:05  – The relationship between compute, capital, and technology11:15 – GPT4 commenting on the technology with help from ElevenLabs Resources: Find Guido on LinkedIn: https://www.linkedin.com/in/appenz/Find Guido on Twitter: https://twitter.com/appenz Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.

With the world constantly generating more data, unlocking the full potential of AI means a constant need for faster and more resilient hardware.In this episode – the second in our three-part series – we explore the challenges for founders trying to build AI companies. We dive into the delta between supply and demand, whether to own or rent, where moats can be found, and even where open source comes into play.Look out for the rest of our series, where we dive into terminology and technology that is the backbone of the AI, how much the cost of compute truly costs! Topics Covered:00:00 – Supply and demand02:44 –  Competition for AI hardware04:32– Who gets access to the supply available06:16– How to select which hardware to use08:39– Cloud versus bringing infrastructure in house12:43– What role does open source play? 15:47– Cheaper and decentralized compute19:04– Rebuilding the stack20:29– Upcoming episodes on cost of compute Resources: Find Guido on LinkedIn: https://www.linkedin.com/in/appenz/Find Guido on Twit